Home Product Biacore

Label-free interaction analysis is of increasing importance for scientists in the academic, pharmaceutical, biotechnology and diagnostic markets. Setting the performance benchmark, Biacore systems generate unique data on the interactions between proteins and other molecules, including small molecule drug candidates. During research, development and manufacture, these data give insights into protein functionality, elucidate disease mechanisms and play a key role in the critical decisions needed for efficient development and production of therapeutics.
Automated Array Format
Biacore A100
"Unique flow systemÀ» °¡Áö°í À־ ÇѹøÀÇ interationÀ¸·Î 20°³ÀÇ data¸¦ ¾òÀ» ¼ö ÀÖ°í, 100Da Á¤µµÀÇ ÀúºÐÀÚ¸¦ detectionÇÒ ¼ö ÀÖ´Â sensitivity¸¦ °¡ÁüÀ¸·Î½á high quality,high information-content interaction study°¡ °¡´ÉÇÑ ÀåºñÀÔ´Ï´Ù.

*Confident selection and optimization of lead compounds
*Early kinetic screening of hybridomas for mAb selection
*Define serum antibody responses in immunogenicity studies and immunotherapeutic development
*Perform large scale functionality studies – proteomics

Biacore Flexchip-Array-based comparative profiling
Kinetics¿Í affinity ÃøÁ¤ÀÌ °¡´ÉÇϰí 400°³ÀÇ spotÀ» °¡Áø protein chipÀ¸·Î½á ºÐÀÚ°£ »óÈ£ÀÛ¿ëÀ» high throughputÀ¸·Î ºÐ¼®ÇÒ ¼ö ÀÖ´Â ÀåºñÀÔ´Ï´Ù.

*Compare and rank hundreds of interactions
*Measure slow association events by using sample recirculation
*Study protein function on a peptide array
*Accelerate interaction-based secondary screening by eliminating bottlenecks in high throughput workflows
*Detect weak, short-lived interactions
*Retain structural integrity and functionality of membrane-bound receptors by using whole cell targets
Automated
Biacore T100
"Kinetics°¡ ¸Å¿ì ¿ì¼öÇϰí 100DaÀÇ ºÐÀÚ¸¦ detectionÇÒ ¼ö ÀÖ´Â sensitivity¸¦ °¡Áø ¸Å¿ì Á¤±³ÇÑ ÀåºñÀÔ´Ï´Ù. Thermodynamics°¡ °¡´ÉÇϰí 4Á¾·ùÀÇ buffer¸¦ »ç¿ëÇÒ ¼ö Àֱ⠶§¹®¿¡ ºÐÀÚ°£ÀÇ °áÇÕ°­µµ¿Í °áÇÕ¼ÓµµÀÇ ÀÌÀ¯¿¡
´ëÇØ ºÐ¼®ÇÒ ¼ö ÀÖ´Â ´Ù¾çÇÑ data¸¦ Á¦°øÇÒ ¼ö ÀÖ½À´Ï´Ù.

*Characterizing native or recombinant protein interactions
*Select the best antibodies by fully defining their interaction behavior
*Define potential drug targets and diagnostic markers
*Characterize protein: LMW compound
*Select protein therapeutic candidates according to their on/off rates
*Detect and characterize immune responses during preclinical and clinical development
*Recover interaction partners for characterization by mass spectrometry
Biacore X100-Ready to run research system - ideal in multi-project, multi-user environments
±âÁ¸ÀÇ BIACORE X¸¦ ±âº»À¸·Î ¸¸µé¾îÁø Àåºñ·Î½á ±âÁ¸ÀÇ manual ¹æ½Ä¿¡¼­ automation À¸·Î ¹Ù²î¾î operationÀÌ ¸Å¿ì simpleÇØÁ³½À´Ï´Ù. Çѹø runningÀ¸·Î 15°³ÀÇ »ùÇÃÀ» automatically ºÐ¼® °¡´ÉÇϰí 200Da Á¤µµÀÇ ÀúºÐÀÚ¸¦ detectionÇÒ ¼ö ÀÖ´Â ÀåºñÀÔ´Ï´Ù.
*Understand molecular mechanisms and interaction pathways *Add function to structure
*Select research tools, diagnostics and therapeutics
*Simple, versatile operation
*Processes up to 15 samples per automated run
*Built-in and web-based support available on-demand 24/7
Biacore 3000-Interaction analysis with SPR-MALDI interface
±âÁ¸ÀÇ BIACORE 2000À» ±âº»À¸·Î recovery ±â´ÉÀÇ Çâ»ó ¹× 180Da Á¤µµÀÇ ÀúºÐÀÚ ¹°Áúµµ detection ÇÒ ¼ö ÀÖµµ·Ï Sensitivity¸¦ ³ô¿´½À´Ï´Ù. kinetic data ¹× affinity, concentrationÀ» ÃøÁ¤Çϴµ¥ ÀÖ¾î perfect ÇÑ °ªÀ» Á¦°øÇØ ÁÙ °ÍÀÔ´Ï´Ù.

*Recover and characterize interaction partners using MALDI MS interface>
*Elucidate disease mechanisms by characterizing native or recombinant protein interactions>
*Define potential drug targets or diagnostic markers>
Automated: dedicated applications
Biacore C-Dedicated for rapid determination of concentration in GxP environments – from preclinical development to QC
ÀüÀÓ»ó´Ü°è³ª QCµî GxP environments¿¡¼­ concentrationÀ» ÃøÁ¤Çϱ⿡ ¿ëÀÌÇϵµ·Ï ¸¸µé¾îÁø ÀåºñÀÔ´Ï´Ù.

Determine active concentrations of protein therapeutics and vaccines
*For in-process control
*For batch release
*For QC
Sensor chips for BIACORE analysis systems
Sensor Chip CM5
°¡Àå ´Ù¾çÇÏ°Ô ÀÀ¿ëÇÒ ¼ö ÀÖ´Â chipÀ¸·Î½á ¼¾¼­Ä¨ Ç¥¸éÀÌ carboxymethylÈ­µÈ µ¦½ºÆ®¶õÀ¸·Î µÇ¾î ÀÖ½À´Ï´Ù. NHS ¶Ç´Â EDC·Î ½±°Ô Ȱ¼ºÀÌ µÇ¸ç, amin coupling¹æ¹ýÀ¸·Î »ý¹°ÇÐÀû Ȱ¼ºÀÇ °¨¼Ò ¾øÀÌ °íÁ¤È­°¡ °¡´ÉÇÕ´Ï´Ù.
Sensor Chip SA
¼¾¼­Ä¨ Ç¥¸é¿¡ StreptavidinÀ» ¹Ì¸® °íÁ¤È­ ½ÃŲ °ÍÀ¸·Î DNA, Polysaccaride, ±×¸®°í ´Ù¸¥ ºñ´Ü¹éÁúÀ» ligand·Î »ç¿ëÇϰíÀÚ ÇÒ ¶§ À¯¿ëÇÕ´Ï´Ù.
Sensor Chip NTA
¼¾¼­Ä¨ Ç¥¸é¿¡ Nitrilotriacetic acid (NTA)À» °íÁ¤½ÃŲ °ÍÀ¸·Î NTA´Â ±Ý¼ÓÀÌ¿Â(NI++)°ú Âø È­ÇÕ¹°À» Çü¼º, »ýü¹°Áú ±¸Á¶³» È÷½ºÆ¼µòÀÌ Á¸ÀçÇÏ¸é ¹èÀ§°áÇÕÀ» Çϱ⠶§¹®¿¡ ¸®°£µå·Î Ĩ¿¡ °íÁ¤È­°¡ °¡´ÉÇÕ´Ï´Ù.
Sensor Chip HPA
¼¾¼­Ä¨ Ç¥¸é¿¡ StreptavidinÀ» ¹Ì¸® °íÁ¤È­ ½ÃŲ °ÍÀ¸·Î DNA, Polysaccaride, ±×¸®°í ´Ù¸¥ ºñ´Ü¹éÁúÀ» ligand·Î »ç¿ëÇϰíÀÚ ÇÒ ¶§ À¯¿ëÇÕ´Ï´Ù.
Sensor Chip L1
¼¾¼­Ä¨ L1Àº lipophilic dextran layer¸¦ Á¦°øÇÏ¿© liposome bilayerÀÇ ÇüŸ¦ °íÁ¤È­ Çϴµ¥ ÀÌ¿ëÇÒ ¼ö ÀÖ½À´Ï´Ù. Membrane conjugated protein À̳ª receptor¿¬±¸¿¡ ÀÖ¾î ÃÖÀûÀÇ Á¶°ÇÀ» Á¦°øÇϸç, GPCRs ¿¬±¸¿¡ À¯¿ëÇÏ°Ô Á¦°øµË´Ï´Ù.
 
More Sensor Chip